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M. S. Biradar

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Open access Sep 2026

Design, Synthesis, In Silico Studies, and HIV‐1 RT Inhibitory Activity of 1,3‐Oxazolidine Pyrimidine Nucleoside Analogues

A series of 1,3‐oxazolidine nucleoside analogues (1‐6) was designed and synthesized for their anti‐HIV activity. The purpose of this study was to determine whether the antiviral activity of the pyrimidine ring is affected by oxazolidine ring substitution. The synthesized compounds were tested for their HIV‐1 RT inhibit...

S. Sriharsha, Zaidi Mohamed, A. A. Razzak Mahmood et al. · 0 citations
Open access 2026

Neuroprotective role of hydroxychloroquine and trimebutine in alzheimer’s disease: Network pharmacology and molecular simulations

An integrated in silico approach consisting of network pharmacology, molecular docking, molecular dynamics simulation, gene expression profiling using AlzData and cell permeability analysis was used to evaluate the therapeutic efficacy of Trimebutine and Hydroxychloroquine against Alzheimer's disease, establishing stab...

Renukaradhya Maharudraiah, K. Kant, Madhusudhan Reddy Alimeneti et al. · 0 citations

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