Author

M. Ranson

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Open access Sep 2026

Neoadjuvant chemotherapy induces transient, regimen-specific immune–stromal reprogramming in pancreatic ductal adenocarcinoma

Background Neoadjuvant chemotherapy (NAC) is increasingly incorporated into the management of pancreatic ductal adenocarcinoma (PDAC), yet how treatment regimen and timing reshape the tumour-immune microenvironment remains poorly defined. Methods Targeted immune transcriptomic profiling was performed using NanoString o...

E. Minaei, D. Cox, A. Thind et al. · bioRxiv · 0 citations