Author

M. Ramsay

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Open access Oct 2026

Causal effects of body mass index on glycaemic traits in African and European populations: a Mendelian randomization study

Aims/hypothesis Higher body mass index (BMI) is associated with higher levels of HbA1c and glucose in conventional observational studies from sub-Saharan Africa, but its causal relationship in this population has not been explored. Mendelian randomization (MR) which leverages genetic variants can strengthen causal infe...

R. Chikwati, Jean-Tristan Brandenburg, D. Sengupta et al. · medRxiv · 0 citations

Open access Sep 2026

Proteomic signatures of BMI generalize across ancestries and reveal cardiometabolic heterogeneity beyond measured BMI

Plasma proteomic scores for body mass index have been derived primarily in European populations, and it is unclear whether these scores are generalizable and useful in other ancestries. Here, we show that plasma proteomic BMI scores developed in participants of European, East Asian, South Asian and African ancestries f...

M. Muti, Y. Ilboudo, U. Aliyu et al. · medRxiv · 0 citations