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Author

M. Radan

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4 papers indexed here

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2026

Harmaline improves diabetes-associated renal alterations in nicotinamide/streptozotocin-induced diabetic mice: Possible involvement of oxidative stress, inflammation, and renin–angiotensin system signaling

Objective(s): Diabetic nephropathy (DN) is marked by structural and functional kidney damage, driven by oxidative stress, inflammation, and renin–angiotensin system (RAS) dysregulation. Harmaline (HAR), a β-carboline alkaloid with potent antioxidant and anti-inflammatory properties, is a promising multi-target therapeu...

Farima Malekinia, Akram Ahangarpour, Khojasteh Hoseinynejad et al. · 0 citations
2026

Protective effect of linalool against morphine-induced renal injury: Modulation of oxidative stress and PI3K/AKT/L-FABP signaling pathway

Objective(s): Opioid misuse and prolonged therapeutic use are increasingly linked to systemic toxicities, including renal dysfunction. Morphine has been shown to induce oxidative stress and disrupt intracellular signaling pathways implicated in kidney injury. Linalool, a naturally occurring monoterpene with antioxidant...

Shokouh Shayanpour, M. Radan, Khojasteh Hoseinynejad et al. · 0 citations
Sep 2026

In Vitro Evidences for Renal-Protective Properties of Phloretin in Nephrotoxicity Induced by Bisphenol-A via Mediation of VCAM-1/ICAM-1 Genes Expression

Phloretin significantly attenuates BPA-induced oxidative stress and inflammation in renal tubular cells, suggesting its potential as a natural nephroprotective agent.

M. Radan, Kousar Mirhashemi, Fereshte Nejaddehbashi et al. · 0 citations
Open access Aug 2026

Potential Involvement of Redox and Inflammatory Signalling in the Antihyperglycemic and Antioxidant Effects of Harmaline in Male Mice With Type 2 Diabetes

Type 2 diabetes mellitus (T2DM) is strongly associated with oxidative stress and inflammation. Harmaline (HAR), an alkaloid with antioxidant and anti‐inflammatory properties, has been suggested to possess antidiabetic potential. This study investigated the effects of HAR in experimental T2DM and its association with ch...

Farima Malekinia, Akram Ahangarpour, Khojasteh Hoseinynejad et al. · 0 citations

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