Cell shape changes during migration, division, or differentiation require the dynamic regulation of actin network mechanics. Actin crosslinkers are central to this regulation, controlling network connectivity and the transmission of contractile forces. A large diversity of crosslinkers exists, differing in length, doma...
Filipe Nunes Vicente, Anumita Jawahar, Michael Wassermair et al.· bioRxiv· 0 citations
The shape of animal cells is controlled by their surface, which comprises the cell cortex, a peripheral actin network, tethered to the plasma membrane by membrane-to-cortex attachment proteins. Changes in cortical components have long been considered to dominate the regulation of forces and mechanical properties at the...
Léanne Strauss, Sergio Lembo, Samuel F. Gérard et al.· Nature Communications· 0 citations
Scaling laws are powerful tools in material science to relate geometric and mechanical properties of materials. The actin cortex, a dynamic network beneath the plasma membrane, is essential for cellular morphogenesis, force generation, and tissue organization. Despite its critical role, the mechanical properties of the...
Joseph Vermeil, Anumita Jawahar, Valentin Laplaud et al.· bioRxiv· 0 citations
Bacterial proliferation in confined spaces occurs in biofilms, intracellular compartments, or infection sites, generating mechanical constraints. We investigated how growth-induced mechanical pressure affects bacterial physiology using a microfluidic device ensuring nutrient access. We found that proliferating Escheric...
Laure Le Blanc, Baptiste Alric, Romain Rollin et al.· Nature Communications· 0 citations
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