Review
Open access
Oct 2026
PP2A targeting: balancing anticancer potential and neurological risk
Protein phosphatase 2A (PP2A) is a multifunctional serine/threonine phosphatase that regulates cell-cycle progression, oncogenic signaling, neuronal development, synaptic homeostasis, and protein proteostasis. Its dysregulation contributes to cancer, whereas impaired PP2A activity in the nervous system is linked to neu...
Margarita Chigriai, N. Kraskovskaya, A. Bolshakova et al.
· Frontiers in Cell and Develo... · 0 citations