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Author

M. Paraizo

2 papers indexed here

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Open access Oct 2026

Baseline Tumor Transcriptional Features and Event-Free Survival After Anti-CD19 CAR T-Cell Therapy with Axicabtagene Ciloleucel in Large B-Cell Lymphoma: An Exploratory Reanalysis of the Randomized ZUMA-7 Trial

Background/Objectives: Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with axicabtagene ciloleucel (axi-cel) improves outcomes in relapsed/refractory large B-cell lymphoma (LBCL), but many patients relapse despite retained CD19 expression. We explored baseline tumor transcriptional features associated with ev...

Jean Silva de Souza Resende, I. S. Giner, Maria Gabriela Custodio de Figueiredo et al. · 0 citations
Review Open access Oct 2026

Clinical and Biological Correlates of Resistance and Relapse After CD19-Directed CAR T-Cell Therapy in Large B-Cell Lymphoma: A Structured Narrative Review

Simple Summary CD19-directed chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment of large B-cell lymphoma (LBCL), but many patients either do not respond or subsequently relapse. This structured narrative review examines clinical outcomes and biological factors associated with resistance and re...

Jean Silva de Souza Resende, I. S. Giner, Maria Gabriela Custodio de Figueiredo et al. · 0 citations

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