M. Panteleev

Dynamics and Regulation of Cyclophilin D-Dependent Necrosis in Platelets

Strong physiological activation of blood platelets leads to the emergence of a non-aggregatable procoagulant subpopulation characterized by the appearance of phosphatidylserine on the outer leaflet of the plasma membrane, providing a surface for coagulation reactions. The formation of procoagulant platelets is attribut...