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Author

M. Palleschi

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Review Open access Sep 2026

Advancing therapies for HER2-positive metastatic breast cancer: Navigating a wealth of treatment options.

The therapeutic landscape of HER2-positive metastatic breast cancer (HER2-positive mBC) has been transformed by increasingly effective HER2-directed therapies. Following the establishment of trastuzumab and pertuzumab as first-line standard treatment, highly active antibody-drug conjugates (ADCs), particularly trastuzu...

M. Palleschi, A. Viansone, Filippo Merloni et al. · 0 citations
Review Open access Jul 2026

Unraveling the use of vaccine therapy in HER-2 positive breast cancer: a comprehensive review of current state and future perspectives

While advanced-stage BC often presents an immunosuppressive tumor microenvironment that hinders vaccine efficacy, early-stage disease offers a more favorable immunological milieu for inducing robust and durable T-cell responses.

A. Caltavituro, C. Martinelli, M. Palleschi et al. · 0 citations

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