OBJECTIVE
We compared demographic and clinical characteristics between patients with late-onset (LO) and early-onset (EO) systemic lupus erythematosus (SLE) and examined their longitudinal associations with treatment targets and long-term outcomes, irreversible organ damage accrual and health-related quality of life (H...
W. Louthrenoo, A. Hoi, V. Golder et al.· Journal of Rheumatology· 0 citations
In this large multicentre cohort, anti-NOR-90 autoantibodies commonly overlapped with other SSc-autoantibodies, and single-specificity anti-NOR-90 positivity was associated with more frequent interstitial lung disease and a tendency for lower mRSS.
Hao Shen, Marie Hudson, S. Proudman et al.· BMC Rheumatology· 0 citations
Systemic sclerosis (SSc) is a multifaceted systemic autoimmune disease, characterised by the interplay of vascular alterations, immune dysregulation, and fibrosis. The molecular changes and the clinical presentation of SSc are highly heterogeneous and vary considerably between individual patients. This heterogeneity ha...
Jörg H. W. Distler, S. Assassi, A. Gabrielli et al.· Annals of the Rheumatic Dise...· 0 citations
Low BMD is highly prevalent in SLE and is strongly influenced by age, GC exposure, and BMI, while HCQ use was linked to a protective effect on bone health, plausibly mediated by anti-resorptive, antioxidant, and glucocorticoid-sparing properties.
Awalia, S. G. Kandinata, Arinditia Triasti Putri et al.· Rheumatology and Immunology...· 0 citations
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