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M. Naveed

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Review Open access Oct 2026

Impact of Evolocumab on LDL‐Cholesterol and Cardiovascular Outcomes in Patients With Established CVD: Systematic Review and Meta‐Analysis

ABSTRACT Background Atherosclerotic cardiovascular disease is a leading cause of morbidity and mortality, and many high‐risk patients fail to reach LDL‐cholesterol (LDL‐C) targets on statins alone. Evolocumab, a PCSK9 inhibitor, offers potent LDL‐C lowering, but a synthesis of its lipid and clinical benefits in seconda...

Anika Goel, M. Naveed, H. Tandel et al. · 0 citations
Meta-analysis Open access Sep 2026

Efficacy and safety of orforglipron 12 mg versus orforglipron 36 mg maintenance dose among patients with obesity with or without diabetes: a systematic review and comprehensive meta-analysis

Obesity is projected to affect about one billion adults by 2030 and is associated with cardiometabolic morbidity. Orforglipron is an oral, non-peptide glucagon-like peptide-1 receptor agonist developed to provide weight and metabolic benefits. Prior meta-analyses have supported its efficacy and safety but were limited...

Mohamed Gamal Hegaz, Mohammad Yassin Al Aboud, Abanoub I. I. Kamel et al. · 0 citations
Review Sep 2026

Efficacy and Safety of Baxdrostat in Hypertension: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Findings strengthen the evidence for selective aldosterone synthase inhibition as a therapeutic approach for aldosterone-mediated hypertension and suggest that baxdrostat may provide an additional treatment option, particularly for patients who remain uncontrolled or cannot tolerate mineralocorticoid receptor antagonis...

Muhammad Burhan, Z. Shahid, M. Naveed et al. · 0 citations
Aug 2026

Impact of Type 2 Diabetes Mellitus on Outcomes Following Transcatheter Aortic Valve Replacement: Insights From a Contemporary US Database.

Patients with T2DM undergoing TAVR demonstrate higher risks of all‐cause mortality, MACCE, and HF exacerbation compared to their counterparts without T2DM. The T2DM cohort also demonstrated higher all‐cause readmissions, mechanical ventilation, and renal replacement therapy compared to patients without T2D...

Hritvik Jain, Nandan Patel, M. Naveed et al. · 0 citations

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