Author

M. N. Muigano

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Open access Sep 2026

Draft genome sequence of Bacillus paranthracis S23, isolated from saline soil of Lake Bogoria, Kenya

ABSTRACT Bacillus paranthracis S23 was isolated from saline soil of Lake Bogoria. Its draft genome, generated using Illumina HiSeq sequencing, comprises 5,583,771 bp across 205 contigs and contains 5,741 predicted protein-coding genes. Genome mining identified biosynthetic gene clusters associated with the production o...

T. B. Wekesa, Grace Kennedy, Damaris Barminga et al. · Microbiology Resource Announ... · 0 citations

Open access Oct 2026

LOL: a Python package for leakage-aware phenotype prediction and confounding diagnostics in GEO transcriptomics datasets

Phenotype prediction from public gene-expression data is straightforward to implement but reliable prediction is harder. Leakage during feature selection can inflate performance estimates. Class imbalance can hide poor performance in minority classes. Confounds like tissue type, repeated sampling, and demographic diffe...

M. N. Muigano · bioRxiv · 0 citations

Review Open access Jul 2026

Functional genetic signatures of the gut microbiome in cardiometabolic diseases: mechanisms and translational opportunities

Across cardiometabolic conditions, a consistent pattern emerges of depletion of beneficial metabolic functions and enrichment of pro-inflammatory and metabolically disruptive pathways, pointing to the importance of microbial functional capacity, rather than taxonomic composition alone, in shaping disease risk and progr...

M. N. Muigano · Frontiers in microbiomes · 1 citation