Author

M. Mirdita

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Open access Oct 2026

Systematic exploration of predicted quaternary structures within pandemic-relevant viral proteomes

Mechanistic understanding of viral protein-protein interactions enables global health security and pandemic preparedness, yet experimental characterisation remains difficult, costly, and often restricted to specialised laboratories. Here, we describe an in silico campaign using AlphaFold2 and AlphaFold-Multimer to pred...

Yew-On Han, Riya Narain, Razan Abbara et al. · bioRxiv · 0 citations

#protein folding Open access Sep 2026

BFVD v3–UniProt-complete, improved viral protein structure predictions

The Big Fantastic Virus Database v3 is the most comprehensive resource for ColabFold-AlphaFold2-predicted viral protein structures, bringing us closer to a structural catalog of the known virosphere and is freely available at bfvd.workers.dev and bfvd.foldseek.com.

R. Kim, O. Pimenova, E. L. Karin et al. · bioRxiv · 0 citations

Open access Jul 2026

Expanding the scope of protein language modeling to protein-protein interactions with MSA Pairformer.

Multiple sequence alignment (MSA) Pairformer is presented, a protein language model that builds on AlphaFold2/3's bidirectional refinement between sequence and pairwise residue representations to accurately model the evolution of protein-protein interactions, despite training exclusively on individual chains.

Yo Akiyama, Zhidian Zhang, Olivia Tang et al. · Cell · 3 citations