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M. Metra

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Open access Aug 2026

Prognostic Value of NYHA Functional Class in Tricuspid Valve Transcatheter Edge-to-Edge Repair: Insights From EuroTR.

BACKGROUND In patients undergoing tricuspid valve transcatheter edge-to-edge repair (T-TEER) for tricuspid regurgitation (TR), NYHA functional class guides assessment, but real-world data on its prognostic value and determinants of symptomatic response remain limited. OBJECTIVES The objective of the study was to asse...

Charlotte Wolff, P. Sagmeister, K. Fengler et al. · 0 citations
Open access Oct 2026

Pharmacological treatment strategies to prevent heart failure across the cardiovascular-kidney-metabolic spectrum: an EJHF Expert Consensus Statement.

Heart failure (HF) remains a major cause of morbidity, mortality, and increased healthcare costs worldwide, and is recognized as the result of progressive cardiovascular-kidney-metabolic (CKM) syndrome. Obesity, type 2 diabetes, chronic kidney disease, hypertension, and atherosclerotic cardiovascular disease frequently...

R. Inciardi, A. Abdin, M. Abdelhamid et al. · 0 citations
Open access Sep 2026

New Evidence in Heart Failure: 2026 Update.

Therapeutic developments continue to reshape HF management across the spectrum of left ventricular ejection fraction, and support the transition from a predominantly phenotype-based approach towards a more personalized and biologically informed model of HF care.

Valentino Liguori, Angelica Rizzello, M. Adamo et al. · 0 citations
Aug 2026

NT-proBNP as a marker of coronary artery disease burden in chronic coronary syndromes.

NT-proBNP was independently associated with obstructive CAD and correlated with coronary disease burden, however, its modest discriminatory performance precludes its use as a stand-alone diagnostic test for high-risk coronary anatomy.

Mirko Schivalocchi, R. Mazza, C. Gaspardone et al. · 0 citations
Review Open access Aug 2026

Mitral Regurgitation in Contemporary Practice: From Diagnosis to Management

An integrated, stepwise management algorithm is proposed that incorporates early risk markers, including natriuretic peptides, to guide the timing of intervention before irreversible myocardial damage occurs and enables more precise patient phenotyping and treatment tailoring.

C. Gaspardone, Paolo Costa, G. Barone et al. · 0 citations

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