Open access
Aug 2026
Spatial transcriptomics reveals site-specific cellular and metabolic heterogeneity in bladder carcinoma in situ
Results demonstrate that CIS exhibits significant intra-patient heterogeneity not captured by single-site profiling, and support multi-region sampling, which could help improve risk stratification, biomarker development, and prediction of response to intravesical therapies.
Tyler D. Myers, A. Salmasi, M. Meagher et al.
· bioRxiv · 0 citations