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M. Marxen

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Open access Sep 2026

Enhanced Alcohol-Specific but not General Pavlovian-to-Instrumental Transfer in Alcohol Use Disorder

Background Pavlovian-to-instrumental transfer (PIT) paradigms assess how environmental cues influence instrumental behaviour. Our previous research linked PIT to alcohol use disorder (AUD) and high-risk drinking using monetary rewards during learning. To better capture alcohol-related cue effects, we developed a PIT pa...

Hao Chen, Christian Bäuchl, L. Thill et al. · 0 citations
Open access Oct 2026

Reduced Control Over Pavlovian-to-Instrumental Transfer in Human Addiction: A Systematic Investigation Across Alcohol Use Disorder and Smoking Status

Pavlovian conditioned stimuli can compromise goal-directed behavior, particularly when they conflict with the required instrumental response. Previous research linked an increased impact of such Pavlovian-to-instrumental transfer (PIT) interference to risky drinking and alcohol dependence. However, it remained unclear...

L. Thill, Hao Chen, Christian Bäuchl et al. · 0 citations
Open access Oct 2026

Impaired Control Symptoms in Alcohol Use Disorder Show Convergent Associations Across Behavioral and Neural Markers of Inhibitory Control and Drinking Behavior

Background Deficits in inhibitory control are considered a central feature of alcohol use disorder (AUD), yet behavioral and neuroimaging findings have been inconsistent. One potential explanation is the marked heterogeneity of AUD, which encompasses multiple symptom dimensions that may differ in their underlying neuro...

J. Böhmer, Pablo Reinhardt, Marco Bottino et al. · 0 citations
Open access Aug 2026

Fluctuations in real-life drinking in alcohol use disorder: A one-year longitudinal study using gamified tasks of decision making and cognitive control.

It is found that smartphone-based, gamified tasks show promise to identify periods of heightened risk paving the way for mechanism-based, real-time interventions in AUD: specific decision-making alterations precede changes in consumption.

Hilmar Zech, Maria Waltmann, D. Reichert et al. · 0 citations
Open access Jul 2026

Changes in resting-state functional connectivity linked to affective symptoms: insights from a population-based study of adolescents and young adults

First episodes of affective disorders often emerge during adolescence and young adulthood. Alterations in resting-state functional connectivity (RSFC) have been reported in affective disorders, yet findings are heterogeneous and associations of RSFC with subclinical affective symptoms in community samples remain limite...

Paula M. Henneberg, Katja Beesdo-Baum, M. Marxen et al. · 0 citations

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