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M. Mapstone

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Open access Oct 2026

Insulin resistance–related metabolic burden, white matter microstructure, and cognitive change: the HABS-HD study

Background Insulin resistance–related metabolic burden is associated with cognitive aging, but the relevant white matter microstructural features remain unclear. We examined statistical indirect associations between metabolic indices and cognition through tract-level white matter measures, including associations with s...

Huai-Yi Li, Zhi-Liang Tian, Xiao-Qian Wang et al. · 0 citations
Open access Aug 2026

Multi-dimensional attention framework for personalised Alzheimer's disease progression prediction across sporadic and genetic risk cohorts

A multi-dimensional attention framework that simultaneously captures both temporal dynamics and biomarker importance to predict disease progression across three fundamentally different populations could enable precision medicine approaches for data-limited cohorts across the Alzheimer's disease spectrum.

Zhi-Yuan Song, Si-Yang Song, Isabel C. H. Clare et al. · 0 citations
Open access Jul 2026

Parallel neuroinflammatory pathways to cerebrovascular burden and amyloid beta in Alzheimer's disease

Higher plasma YKL‐40 was associated with greater white matter hyperintensity (WMH), whereas higher plasma GFAP was related to increased 18F‐florbetapir (FBP) standardized uptake value ratio (SUVR) and higher plasma p‐tau217 was associated with reduced MTL cortical thickness and hippocampal volume.

Batool Rizvi, Jenna N. Adams, Alison R. Bamford et al. · 1 citation

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