In vitro proof-of-concept feasibility of SMART-assisted hydrogel encapsulation as an ambient-temperature-stable platform for microbial antigen production is demonstrated and provides a foundation for future development of biomanufacturing systems that may help reduce cold-chain dependence.
Shao-Ching Feng, Prashant Pandey, L. R. J. Chakka et al.· ACS Omega· 0 citations
Thermal extrusion is a well-established approach for producing amorphous solid dispersions (ASDs) to enhance the solubility, dissolution, and bioavailability of poorly water-soluble drugs. Atorvastatin calcium trihydrate (ACT), a BCS class II lipid-lowering agent, exhibits low aqueous solubility, limited oral bioavaila...
T. R. Anekalla, Sujith Raj Bashetty, Navya Nalajala et al.· AAPS PharmSciTech· 0 citations
This review consolidates current advances in exosome biology, including their biogenesis, isolation, characterization, and engineering for antimicrobial applications, and identifies EV-based systems may help address selected antimicrobial resistance (AMR) challenges by enabling delivery of antibiotics, antimicrobial pe...
Y. Choonara, K. Mnqiwu, M. Chougule et al.· International journal of pha...· 0 citations
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