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Open access Sep 2026

Thiolactomycin-based morpholino and piperidino conjugates: synthesis, antimalarial evaluation, and PfFAS-II inhibition

Background and purpose: Malaria remains a formidable global healthcare challenge due to emerging drug-resistant Plasmodium spp., underscoring the urgent need for novel antimalarial scaffolds. Thiolactomycin, a FAS-II inhibitor, is a promising lead for structural optimization. This study aims to design, synthesize, and...

Shaik Azeeza, M. Malik, Q. M. Jamal et al. · 0 citations

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