Lung cancer (LC) is the leading cause of cancer mortality worldwide. Beyond pharmacological advances, lifestyle interventions such as exercise and nutrition have emerged as valuable adjuvant strategies. Preclinical and translational studies suggest that exercise may modulate molecular and immune pathways relevant to tu...
A. Cardeña-Gutiérrez, Teresa García Manrique, Laura Gutiérrez Sainz et al.· Clinical and Translational O...· 0 citations
INTRODUCTION
In ADAURA, adjuvant osimertinib improved DFS and OS versus placebo in resected EGFR-mutated stage IB-IIIA NSCLC. We report a post hoc exploratory analysis of long-term OS post-adjuvant treatment completion.
METHODS
Patients (N = 682) were randomized to osimertinib or placebo until recurrence, treatment c...
Yi-Long Wu, M. Majem, T. John et al.· Journal of Thoracic Oncology· 1 citation
BACKGROUND
Adding perioperative pembrolizumab to neoadjuvant chemotherapy significantly improved survival outcomes compared with neoadjuvant chemotherapy and surgery alone in participants with early-stage non-small-cell lung cancer (NSCLC) in the phase 3, randomized KEYNOTE-671 study. We report results from KEYNOTE-671...
H. Wakelee, J. Spicer, S. Gao et al.· Annals of Oncology· 1 citation
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