Author

M. Linial

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Open access Aug 2026

Spliceosomal miR-99b Regulates SPACA6-AS1 Pre-mRNA Levels and Promotes Malignant Phenotypes in Breast Cancer

A novel nuclear function of miR-99b is uncovered in modulating lncRNA splicing and gene expression, which represents a previously unrecognized regulatory pathway that contributes to breast cancer progression and may provide a potential target for diagnostic and therapeutic strategies.

Aya Muharram, Maram Arafat, M. Linial et al. · bioRxiv · 0 citations

Open access Aug 2026

Micropeptides encoded by lncRNAs associated with cancer progression reveal novel immunogenic epitopes

Dipeptide composition and conservation analyses showed that these MPs differ from a size-matched human coding proteome, supporting their potential as neoantigens, highlighting their promise as biomarkers and targets for immunotherapy.

Stav Zok, M. Linial · Bioinformatics · 0 citations

Open access Jul 2026

Signatures of micropeptides encoded by lncRNAs in cancer progression and metastasis.

Tr-lncRNA-derived MPs represent a previously underexplored class of potentially functional molecules associated with cancer clinical annotation and may serve as biomarkers for disease progression.

Stav Zok, M. Linial · British Journal of Cancer · 1 citation