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Author

M. Lemaître

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Open access Aug 2026

MBNL depletion drives stem cell fusion and immature myonuclear states in myotonic dystrophy type 1

It is shown that muscle stem cells are activated and fuse with existing muscle fibres in myotonic dystrophy type 1, producing centrally located nuclei with altered gene-expression states and reshaping diseased muscle.

Vanessa Todorow, X. Lornage, Shinichiro Hayashi et al. · 0 citations
Open access Aug 2026

Axonopathy in Duchenne Muscular Dystrophy limits microdystrophin gene therapy efficacy

DMD is redefined as an integrated motor unit pathology, thereby underscoring the absolute necessity of implementing combined therapeutic strategies that target both the muscle and the peripheral nervous system.

Aly Bourguiba-Villeneuve, Maxime Gelin, Aurélie Fail et al. · 0 citations

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