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Sep 2026

Exposure to di(2-ethylhexyl) phthalate and diisononyl phthalate alters the aryl hydrocarbon receptor signaling pathway in the ovary throughout reproductive aging in mice.

Di(2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DiNP) are plasticizers used in many consumer products. Both phthalates alter estrous cyclicity, fertility indices, and folliculogenesis throughout the reproductive lifespan. Our companion paper showed that exposure to a phthalate mixture containing DEHP and Di...

A. E. Dean, R. Santacruz-Márquez, A. Safar et al. · 0 citations
Open access Aug 2026

Chronic Di(2-ethylhexyl) phthalate and Diisononyl phthalate Exposure Impairs Uterine Endometrial Glycogen Metabolism in Mice.

Results show that phthalates alter endometrial glycogen levels and expression of key enzymes, which are consistent with altered glycogen metabolism, which could alter endometrial glucose metabolism.

P. Zarei, Isabella Raneri, Garima Thapa et al. · 0 citations
Open access Jul 2026

Acute Exposure to Di(2-ethylhexyl) Phthalate or Diisononyl Phthalate Leads to Increased Inflammation and Oxidative Stress in the Uteri of Mice.

Phthalates are a class of synthetic compounds, known as endocrine-disrupting chemicals, widely used as plasticizers in consumer products, including personal care items, medical devices, and food packaging. Two common phthalates, di(2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DiNP), have been associated wit...

Adriana Andrus, L. Y. Parra-Forero, Coba N Sexton et al. · 1 citation

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