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Author

M. Laschke

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#protein folding Open access Oct 2026

Physiologically based pharmacokinetic modeling as a translational tool in forensic toxicology: from pig to human synthetic cannabinoid toxicokinetics using 5F-Cumyl-P7AICA and its major metabolite as a case study.

A PBTK model was developed for 5FC and its primary metabolite N-pentanoic acid in pigs and translated to humans for predicting systemic and tissue-specific exposure and generated exploratory human systemic and tissue exposure predictions.

Omar Zaher, D. Selzer, H. Loer et al. · 0 citations
Open access Sep 2026

Inflammasome expression patterns during bone regeneration: predictive biomarkers and potential therapeutic targets in non-union formation

Background Non-union formation is one of the major complications in trauma and orthopedic surgery. The inflammatory response at the fracture site is crucial for determining the healing outcome. However, there is limited information on the expression profiles of inflammasomes during both successful fracture repair and n...

Maximilian M. Menger, Oguzhan Nakisli, Benedikt Braun et al. · 0 citations

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