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Open access Sep 2026

Using mixtures of linoleic acid, a long-chain polyunsaturated fatty acid, and its monoglyceride in lipid-based formulations to increase drug loading and enhance aqueous microemulsification.

Although lipid-based formulations (LBFs) of self-emulsifying drug delivery systems (SEDDS) have been used for poorly water-soluble drugs, they have many limitations, the first being the low solubility of drugs in lipids, which limits drug loading in formulations, and the second being inadequate dispersion of formulatio...

Hari P. Kandagatla, Nower Chowdhury, Tatjana Ž. Verbić et al. · 0 citations
Open access Sep 2026

In vitro evaluation of water-insoluble silicates and polyvinylpyrrolidone-vinyl acetate as oral carriers for amorphous ritonavir: dissolution enhancement and the role of phosphatidylcholine.

Porous silicates have been investigated as drug carriers to promote the solubility and in vitro dissolution of poorly water-soluble drugs, owing to their potential to adsorb drug molecules in the amorphous form within their structural cavities. This study aimed to evaluate the efficiency of bentonite (BT), Aeroperl 300...

Gaurav Dhumal, Adélaïde Savoy, M. Kuentz et al. · 0 citations

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