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M. Kramer

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Open access Sep 2026

Extrahepatic Autoimmune Disease in People With Primary Biliary Cholangitis: Nationwide Occurrence and Relation to Outcome.

BACKGROUND AND AIM Primary biliary cholangitis (PBC) is associated with several extrahepatic autoimmune diseases (EHAIDs), but reliable prevalence estimates are scarce. We determined the occurrence of EHAIDs in a nationwide population with PBC and their association with outcome. METHODS The retrospective Dutch PBC Co...

Gemma H. X. Weijsters, E. Werner, Tiki Blom et al. · 0 citations
Open access Sep 2026

Thrombin dynamics and clinical events in cirrhosis: low prothrombin conversion predicts bleeding risk

Pro- and anti-coagulant factors are significantly altered in liver cirrhosis resulting in an increased bleeding and thrombosis risk. The thrombin generation (TG) test often seems unaltered in cirrhosis, indicating that a new hemostatic balance is reached. TG is determined by prothrombin conversion and thrombin inactiva...

R. Willems, A. Zanetto, E. Campello et al. · 0 citations

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