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Author

M. Koch

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2 papers indexed here

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Open access Sep 2026

Sclerostin regulates bone morphogenetic protein (BMP) bioavailability through interactions with BMP complexes and fibrillin microfibrils.

Sclerostin (SOST) is a secreted glycoprotein that antagonizes Wnt and BMP signaling, however, the molecular mechanisms regulating its extracellular distribution and growth factor (GF) interactions remain poorly understood. Here, we identify fibrillin microfibrils as high-affinity extracellular binding partners of SOST....

Annkatrin Correns, Fady Marcous, Steffen Lütke et al. · 0 citations
Open access Aug 2026

A case of Bundibugyo virus disease treated with monoclonal antibodies and remdesivir.

Clinical data on Bundibugyo virus (BDBV) infection are limited, and no approved virus-specific treatment exists. We describe the case of a previously healthy 39-year-old healthcare worker who acquired BDBV infection while working in Ituri Province, Democratic Republic of the Congo (DRC), and was medically evacuated to...

Alexander Uhrig, Frieder Pfäfflin, P. Tober-Lau et al. · 1 citation

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