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Key Points Question What is the association among preterm risk factors, epigenetic aging, and neurodevelopmental outcomes in children born preterm? Findings In this cohort study with 102 children, epigenetic aging, higher maternal education level, extreme prematurity, and severe brain injury were associated with neurod...
DNA methylation (DNAm)-based tools are predominantly developed in European ancestry, high-income populations, raising questions on their applicability in diverse and rural settings, and it is found no significant contribution to genome-wide DNAm or predictive sites used in these tools are found.
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