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Open access Oct 2026

Recurrence After Resection of Colorectal Liver Metastases and Its Impact on Survival: A Multistate Model-Based, Multi-institutional Observational Cohort Study.

BACKGROUND Conventional survival analyses cannot fully account for recurrence as an intermediate event that dynamically influences subsequent mortality. Multistate models (MSMs) enable explicit modeling of transitions between clinically relevant disease states; however, their application among patients undergoing resec...

Andrea Baldo, Miho Akabane, C. Charalampous et al. · 0 citations
Open access Sep 2026

UBQLN4 Is a Prognostic Biomarker in Intrahepatic Cholangiocarcinoma That Is Associated with Cisplatin Resistance

Highlights What are the main findings? Ubiquilin-4 (UBQLN4) mRNA expression was significantly elevated in intrahepatic cholangiocarcinoma (iCCA) compared to normal liver tissue. Elevated UBQLN4 mRNA expression was associated with shorter recurrence-free and overall survival across independent multicenter iCCA patient c...

Kodai Abe, Kelly Chong, Yuta Abe et al. · 0 citations

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