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BACKGROUND Arsenic has a significant role in the pathogenesis of neurological disorders. Rosmarinic acid (RA) is a naturally occurring phenolic compound known for its antioxidant and anti-inflammatory activities. The present study aims to explore the effects of RA against neurotoxicity caused by sodium arsenite (SA) ex...
The research investigates the neuroprotective effects of Linagliptin (Lina), a dipeptidyl peptidase-4, against the neurotoxic impacts of Mancozeb (MNZ), which is known to cause cognitive deficits and oxidative stress. Methods: The study involved six groups of rats, with behavioral assessments conducted through va...
Background and purpose: Paraquat (PQ) is a toxic herbicide to humans and animals that causes kidney damage. Ketotifen (KTF) is a first-generation antihistamine and a potent mast cell stabilizer with antioxidant and anti-inflammatory properties. This study aimed to evaluate the protective effect of KTF against PQ-induce...
It is demonstrated that LOS can protect PC12 cells from ACR-induced neurotoxicity by enhancing antioxidant defenses and modulating apoptotic signaling.
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