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Sep 2026

Investigation of overnight growth hormone secretion patterns in the clinical diagnosis of growth hormone neurosecretory dysfunction.

OBJECTIVE Growth hormone neurosecretory dysfunction (NSD) is a clinical condition characterized by impaired spontaneous, particularly nocturnal, growth hormone (GH) secretion despite a normal response to pharmacological GH stimulation tests. This study aimed to compare overnight GH secretion patterns between children w...

Nurgül Ataş, M. Kopan, Fatoş Çirkin Melik et al. · 0 citations
Open access Oct 2026

Endocrine Phenotype and GH1 Sequence Variation in Children with Short Stature: Five-Year Growth Outcomes of Growth Hormone Therapy

Background: Growth hormone (GH) stimulation tests have limited diagnostic precision in childhood short stature (SS), and the relationships among endocrine phenotype, GH1 variation, and long-term treatment response remain unclear. We examined the clinical, endocrine, genetic, and five-year growth outcomes of children re...

S. Albayrak, M. Karaoğlan, Ahmet Yıldırım et al. · 0 citations

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