M. Kanai

sc-pcQTL: hurdle-based co-expression modeling for multi-gene QTL mapping in single-cell RNA-seq data

The developed sc-pcQTL complements conventional single-gene eQTL analysis by identifying trait-relevant regulatory signals shared across neighboring genes and summarizes each cluster using principal components, and maps cis-pcQTLs.

Genome-wide association analyses of gestational phenotypes identify context-specific genetic effects