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Author

M. K. Katiyar

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Open access Aug 2026

Structural and mechanistic analysis of semisynthetic α-mangostin derivatives with anticancer activity via topoisomerase II inhibition.

Eleven novel alkyl/arylalkyl substituted α-mangostin derivatives (M2-M12) were synthesized from isolated α-mangostin (M1) from the pericarp of Garcinia mangostana L. extract. Among all the compounds, M10 exhibited the most potent antiproliferative activity against MCF-7 cells, with an IC₅₀ of 8.39 ± 0.07 μM, comparable...

M. K. Katiyar, Faheem Ahmed, Sonali Priyadarshini et al. · 0 citations
#protein folding Sep 2026

Decoupling viscosity induced fluorescence from HSA-induced absorption modulation in a chromyl-naphthyl molecular rotor.

Molecular rotors are valuable probes for studying local microenvironments because their optical behavior is closely linked to conformational dynamics. In this study, a chromyl-naphthyl (HCNP) donor-π-acceptor molecular rotor was developed for viscosity-responsive fluorescence and selective interaction with human serum...

Anju Ranolia, L. Narayan, M. K. Katiyar et al. · 0 citations

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