BACKGROUND
Fatty liver is the most common chronic liver disease globally and is associated with increased cardiovascular risk. Evidence specifically addressing fatty liver and cardiovascular outcomes in young adults from European population-based cohorts remains scarce.
METHODS
Fatty liver was assessed by abdominal u...
O. Raitakari, K. Pahkala, S. Rovio et al.· Atherosclerosis· 0 citations
Late diagnosis of type 2 diabetes increases patient morbidity and healthcare burden, yet current prediction models use adult risk factors to estimate 5–10-year risk. In this manuscript, we evaluate long-term prediction of type 2 diabetes over 38 years using childhood factors and polygenic risk scores (PRSs). Data fro...
Rooholla Poursoleymani, Ioannis Papathanail, Lorenzo Brigato et al.· Scientific Reports· 0 citations
Inverse associations between Lp(a) and fasting glucose were observed in males and higher adult Lp(a) concentrations were prospectively associated with lower risk of incident type 2 diabetes, in the prospective Young Finns Study cohort.
M. Knuuti, N. Kartiosuo, K. Pahkala et al.· Cardiovascular Diabetology· 0 citations
An LE8-derived DNAm score was associated with lower cIMT across the life course and, to a lesser extent, across generations, suggesting that blood DNAm reflects cumulative cardiovascular health and vascular burden and may complement conventional cardiovascular risk assessment.
B. Mishra, E. Raitoharju, L.-P. LyytikaÌinen et al.· medRxiv· 0 citations
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