Enhanced Dissolution and Oral Bioavailability of Tegoprazan Using D-α-Tocopheryl Polyethylene Glycol 1000 Succinate-Based Melt Granulation System
The crystalline drug-loaded TPGS-based MG represents a promising strategy for improving the oral delivery of TPZ, and exhibited robust physicochemical stability, showing no drug degradation, changes in dissolution behavior, or crystalline alterations.