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Open access Sep 2026

Enhanced Dissolution and Oral Bioavailability of Tegoprazan Using D-α-Tocopheryl Polyethylene Glycol 1000 Succinate-Based Melt Granulation System

The crystalline drug-loaded TPGS-based MG represents a promising strategy for improving the oral delivery of TPZ, and exhibited robust physicochemical stability, showing no drug degradation, changes in dissolution behavior, or crystalline alterations.

M. Jeong, Tae Hyoung Kim, I. Yang et al. · 0 citations
Aug 2026

Ready-to-use, spheronized drug particles-embedded iron(III)-reinforced carboxymethyl cellulose hydrogels as novel long-acting injectable platform with reduced local inflammation.

This study aimed to construct a ready-to-use, spheronized drug particle-embedded iron(III)-reinforced carboxymethyl cellulose hydrogel (Fe3+-CMC HG) as a novel long-acting injectable (LAI) platform for hydrophobic drugs. Dutasteride (DTS), a lipophilic 5α-reductase inhibitor prescribed for benign prostatic hyperplasia,...

Min Young Jeong, D. Shin, I. Yang et al. · 0 citations

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