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Open access Oct 2026

GnRH antagonist-induced ovarian suppression does not protect the ovarian reserve from cyclophosphamide chemotherapy in tumour-bearing mice

Gonadotropin-releasing hormone (GnRH) analogues are used clinically to induce ovarian suppression during chemotherapy treatment and are proposed to protect the ovaries from chemotherapy-induced damage, yet their efficacy and underlying mechanisms remain uncertain. While most preclinical and clinical studies have fo...

Y. Lewis, Daniella Herszberg, Kate Fowler et al. · 0 citations

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