M. Herrera

NAD⁺ modulation by nicotinamide riboside enhances CD8⁺ T-cell metabolic fitness and effector function during Trypanosoma cruzi infection and improves parasite control

Chagas disease, caused by the parasite Trypanosoma cruzi, remains a major health concern, with effective immune control relying heavily on CD8⁺ T cells. However, the metabolic factors that regulate CD8⁺ T cell function during infection are not well understood. Acute T. cruzi infection induced metabolic remodeling in pa...