Author

M. Helal

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Open access Aug 2026

Synthesis and molecular docking of novel pyrazole, pyrimidine, and pyridine derivatives as potent antimicrobial, antibiofilm, and anticancer agents

Overall, the functionalized heterocycles, particularly compounds 4 and 13, represent promising dual-acting candidates with potent antibacterial, antibiofilm, and selective anticancer activities.

A. Hassan, E. Essam, Selwan Hamed et al. · Scientific Reports · 0 citations

Jul 2026

Insights into novel benzo[h]quinoline-based 2-thioxothiazolidin-4-one and thiazol-4-one hybrids as potential antimicrobial, and antibiofilm candidates: Design, synthesis, molecular modeling, and in-silico ADME studies.

The findings strongly confirm the substituted benzo[h]quinoline core as a highly promising pharmacophore for the development of next-generation antimicrobial medicines effective against both free-floating planktonic cells and tough structured biofilms.

Reham R Raslan, S. Eissa, Moustafa S. Abusaif et al. · Bioorganic chemistry (Print) · 0 citations