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Open access Sep 2026

SEDATION DIFFERENTIALLY AFFECTS DISTORTION-PRODUCT AND STIMULUS-FREQUENCY OTOACOUSTIC EMISSIONS IN CHINCHILLAS

Purpose Otoacoustic emissions (OAEs) are used to assess outer hair cell (OHC) function. Clinical interpretation of OAE responses, however, is often limited to a present/absent binary since both physiological factors and measurement variability affect the measured OAE amplitude. Prior work showed elevated OAE responses...

Samantha N. Hauser, A. Sivaprakasam, Hari M. Bharadwaj et al. · 0 citations
Open access Aug 2026

Ototoxicity-induced inner-hair-cell specific dysfunction degrades neurometric modulation detection in noise without altering peripheral tuning

Sensorineural hearing loss can result from different pathologies, but the primary diagnostic method is a threshold-based audiogram, which is insensitive to some forms of cochlear dysfunction. Individuals may experience difficulty understanding speech in noise despite normal audiometric thresholds. Because most cochlear...

D. Axe, V. Muthaiah, Afagh Farhadi et al. · 0 citations

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