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M. Heiland

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Open access Sep 2026

Incidental Findings on Large-Field-of-View Cone Beam Computed Tomography Scans: Prevalence, Anatomical Distribution and Predictors of Clinical Relevance in a Retrospective Analysis of 203 Patients

Objectives: This study aimed to assess the prevalence, anatomical distribution, and clinical relevance of incidental findings in large-field cone beam computed tomography (CBCT) scans and to identify patient-related predictors associated with their occurrence. Methods: We conducted a retrospective analysis of 203 patie...

Oliver Heidepriem, S. Preissner, Meikel Vesper et al. · 0 citations
Oct 2026

Frailty as a Predictor of Outcomes After Fibula Free Flap for Head and Neck Reconstruction: A Multi-Institutional Analysis Using the mFI-5.

BACKGROUND Chronological age inadequately reflects physiologic vulnerability in older adults undergoing complex reconstruction. Frailty, quantified by the 5-item Modified Frailty Index (mFI-5), may better stratify perioperative risk in fibula free flap (FFF) reconstruction for head and neck defects, but its impact rema...

Wei-Tee Jia, D. Matar, Lorenzo Puppi et al. · 0 citations
Open access Sep 2026

Deep learning-driven analysis of osteotomy gap healing following mandibular bilateral sagittal split osteotomy.

Bone healing across the osteotomy gap after bilateral sagittal split osteotomy (BSSO) determines whether osteosynthesis material can be safely removed, but is traditionally assessed by subjective visual inspection of cone-beam computed tomography (CBCT) images. This study aimed to develop and validate a deep learning-b...

M. Alfertshofer, Kento Odaka, S. Bigus et al. · 0 citations
Open access Aug 2026

Programmed Death-Ligand 1 (PD-L1) expression and clinical outcomes in oral squamous cell carcinoma: evidence from a large clinical cohort

Despite the recognized biological relevance of the PD-1/PD-L1 axis in immune evasion, the prognostic significance of PD-L1 expression in surgically treated oral squamous cell cancer (OSCC) patients remains largely unclear. To investigate the prognostic significance of PD-L1 expression in a large cohort of OSCC patients...

M. Alfertshofer, M. Richter, K. Klinghammer et al. · 0 citations
Open access Sep 2026

Automated assessment of aesthetic outcomes following combined facial aesthetic surgery – a pilot study

Outcomes after combined facial aesthetic surgery (CFAS), defined as the simultaneous performance of two or more facial rejuvenation procedures in a single operative setting, are commonly evaluated using subjective tools with high interrater variability. This pilot feasibility study aimed to explore a quantitative, auto...

Khalil Sherwani, L. Knoedler, Thomas Schaschinger et al. · 0 citations
Open access Sep 2026

Surface-engineered WE43 magnesium implants promote bone repair and reshape the peri-implant immune microenvironment.

PEO is associated with a less pro-inflammatory peri-implant immune profile at day 28, and improved bone healing parameters, which inform the design of immunomodulatory, degradable implants to improve bone healing.

C. Bucher, H. Fischer, A. Ellinghaus et al. · 1 citation
Review Open access Aug 2026

AI-based tools for predicting and early diagnosis of graft rejection in solid organ transplantation - a systematic review.

AI models using ML and DL may show strong potential, particularly in kidney transplantation, for non-invasive early detection of active graft rejection and prediction of future rejection risk, across diverse data types.

Douglas Henderson, Tobias Niederegger, R. Munzinger et al. · 0 citations

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