Aug 2026
Synthesis, multi-target enzyme inhibition, and in silico evaluation of phthalimide derivatives with relevance to tuberculosis-associated pathophysiology.
A new series of phthalimide derivatives was synthesized and structurally characterized through 1H NMR and 13C NMR, with further optimization performed at the DFT level, identifying C15 and C17 as promising lead compounds for further optimization as multitarget enzyme inhibitors.
A. Khushal, Sara Khan, Umar Farooq et al.
· Bioorganic chemistry (Print) · 0 citations