Immune Checkpoint Inhibition in Locally Advanced, Recurrent, and Metastatic Cutaneous Squamous Cell Carcinoma.
Cutaneous squamous cell carcinoma (cSCC) is a potentially aggressive non-melanoma skin cancer with rising incidence attributed to ultraviolet radiation exposure, chronic inflammation, aging, immunosuppression, and improved detection technology. Immune checkpoint inhibitors (ICIs) have transformed treatment for advanced...