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Author

M. Giladi

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Sep 2026

Abstract B071: Preclinical Evaluation of Tumor Treating Fields (TTFields) Applied with KRAS Inhibitors in Pancreatic Ductal Adenocarcinoma Models

Pancreatic ductal adenocarcinoma (PDAC) remains among the most lethal malignancies, with limited survival despite advances in systemic therapy. Activating KRAS mutations, present in approximately 90% of PDACs, contribute to tumor progression in part through regulation of c-Myc. Tumor Treating Fields (TTFields) therap...

H. Fishman, Y. E. Mutlak, L. Lifshitz et al. · 0 citations
Open access Sep 2026

Mice with the mono-allelic p.R37H Dhdds variant show aberrant glycosylation and interneuron deficits

The results define cis-PTase as a master regulator of CNS development and function and establish that its monoallelic debilitating variants cause a novel congenital disorder of glycosylation associated with aberrant levels of neuronal proteins and lipids.

Afitz Da Silva, Merrick S. Fallah, Samuel Boris Tene Tadoum et al. · 0 citations
Case report Open access Jul 2026

Further Support for Association of DAND5 with Autosomal Recessive Laterality Disorders

These findings further support biallelic loss of function variants in DAND5 autosomal recessive laterality defects and suggest DAND5 has recently been suggested as a candidate gene in heterotaxy and CHDs.

O. Chorin, Yoav Bolkier, Uriel Katz et al. · 0 citations

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