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M. Filizola

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Open access Oct 2026

Mechanistic basis for the selective recognition of the Fcγ receptor IIa by monoclonal antibody IV.3.

The monoclonal antibody IV.3 selectively binds the platelet Fcγ receptor IIa (FcγRIIa), potently blocking immune complex engagement without cross-reacting with the closely-related FcγRIIb. This specificity has made IV.3 invaluable for dissecting FcγRIIa-mediated activation in diverse conditions, including infection, au...

Jia-Ling Wang, Sabina Novack, Ji-Hong Li et al. · 0 citations

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