Lactiplantibacillus plantarum CRL1506 ameliorates poly(I:C)-induced acute liver injury through cell wall-dependent modulation of inflammatory and antiviral immune responses.
Acute viral hepatitis is characterized by excessive inflammatory and antiviral immune responses that contribute to liver injury. Polyinosinic-polycytidylic acid [poly(I:C)], a synthetic analog of viral double-stranded RNA, is widely used to mimic virus-induced acute liver damage. Increasing evidence indicates that immu...