Summary Academic treatment optimization studies (TOS) play an important role in determining how established and emerging treatments should be combined, sequenced, intensified, de-intensified, or otherwise optimized in routine clinical care. Unlike commercial clinical trials, which primarily support the development and...
W. E. Berdel, M. Dreyling, M. Schrappe et al.· The Lancet Regional Health -...· 0 citations
For patients with large B-cell lymphoma progressing after multiple lines of therapy few treatment options remain, including the new CD19-directed antibody-drug conjugate loncastuximab tesirine (lonca). To further elucidate its efficacy and safety, we conducted a real-world analysis including data from 31 German centers...
Evgenii Shumilov, Lina J. Kolloch, Philipp Faustmann et al.· Blood Advances· 0 citations
Patients with malignant lymphomas are at increased risk for severe COVID-19. In the general population, outcomes of COVID-19 have improved dramatically over time due to increasing immunity through vaccination or infection and due to improved clinical care. It is unclear whether outcomes of COVID-19 in patients with lym...
Stefanie Forkl, Felix Freudenberger, Benedikt Jacobs et al.· Annals of Hematology· 0 citations
This phase 1 dose-escalation part of the ATALANTA-1 phase 1/2, single-arm study was executed in five hospitals in the Netherlands and Belgium to evaluate the safety and determine the recommended phase 2 dose of GLPG5101.
M. Kersten, M. Kuipers, P. Mutsaers et al.· The Lancet Haematology· 0 citations
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