M. Desai

Assessing the pathogenic potential of PIK3CA gene variants in human cancer using a computational approach.

The phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (p110α) is a key lipid kinase encoded by PIK3CA gene that regulates multiple intracellular signaling pathways. The nsSNPs within PIK3CA can alter protein structure and function, thereby influencing cellular processes and increasing susceptibilit...