Author

Marianne K. DeGorter

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Open access Nov 2026

Multi-omics in the All Of Us Research Program expands mapping genetic mechanisms in health and disease

The All of Us (AoU) Research Program multi-omics cohort was developed to expand discovery of the molecular mechanisms underlying health and disease. Here, we report on the AoU multi-omics cohort comprising proteomic (N = 10,043) and transcriptomic (N = 9,043) sequencing data generated from ancestrally diverse AoU parti...

E. Padhi, E. Kiernan, Jonathan Nguyen et al. · medRxiv · 0 citations

Open access Jul 2026

Pangenome-based human genome analysis improves trait association and genomic prediction

A graph-based method for associating sequence variation with traits using short-read genome sequencing data, and shows that it captures complex forms of genetic variation missed by other methods, suggest that integration of pangenomic methods into human genetic studies will improve trait association and genomic predict...

Shuangjia Lu, Wen-Wei Liao, Marianne K. DeGorter et al. · bioRxiv · 0 citations