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Author

M. Chrysanthou-Piterou

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2 papers indexed here

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Open access Sep 2026

Spatial transcriptomics reveals early and progressive molecular changes in late-onset Pompe disease muscle

Spatial transcriptomics indicated that mitochondrial dysfunction, oxidative stress responses, pro-apoptotic stress signalling, and p38-associated stress-response signalling are early features of Pompe muscle, and patient-level PCA further identified a severity-associated transcriptomic continuum.

Alexandra Monceau, E. Gallardo, A. Hernández-Laín et al. · 0 citations
Oct 2026

Evidence of a redox-dependent regulation of satellite cell activity and regeneration in human skeletal muscle following aseptic injury: a randomized controlled trial.

Satellite cells are essential for skeletal muscle regeneration, with their activity tightly regulated by glutathione (GSH) metabolism and redox balance. Effective regeneration requires an optimal redox hormetic range and balanced GSH levels, as both oxidative and reductive distress can impair redox signaling, satellite...

Konstantinos Papanikolaou, A. Jamurtas, D. Draganidis et al. · 0 citations

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