Author

M. Canevelli

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Open access Sep 2026

Exploring the interplay between frailty, Alzheimer's disease biomarkers, and cognitive functioning in patients with mild cognitive impairment: A cross-sectional study.

BackgroundFrailty is characterized by declining homeostatic reserves and increased vulnerability to stressors, and has been associated with cognitive decline and dementia.ObjectiveTo examine the relationship between frailty, Alzheimer's disease (AD) biomarkers, and cognitive performance in individuals with mild cogniti...

Manuela Pintus, M. Valletta, L. Sacchi et al. · Journal of Alzheimer's Disea... · 0 citations

Review Open access Sep 2026

Sociodemographic and clinical characteristics of participants in blood p-tau217 studies for Alzheimer's disease: A systematic review.

Overall, current evidence on p-tau217 is derived mainly from selected populations and may not fully reflect real-world clinical diversity, so future studies should prioritize more representative cohorts and standardized reporting of key variables will be essential to strengthen its adoption in clinical practice.

M. T. Blasi, Simona Buscarnera, M. Salzillo et al. · Ageing Research Reviews · 0 citations

Open access Jul 2026

Blood Biomarkers of Alzheimer's Disease and Patterns of Structural Brain Changes in the Community.

In cognitively unimpaired older adults, elevated blood p-tau217 was linked to faster shrinkage in AD-specific brain regions, whereas NfL and GFAP were associated with more widespread atrophy, with NfL also associated with accelerated WMH accumulation.

Martina Valletta, D. L. Vetrano, E. J. Laukka et al. · Annals of Neurology · 0 citations